VThunter

a database for single-cell screening of virus target cells in animal kingdom

Mongolian horse

Scientific Name: Equus caballus

Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Laurasiatheria-> Perissodactyla-> Equidae-> Equus-> Equus

Human betaherpesvirus 6B

Family: Herpesviridae

Receptor: TNFRSF4

Receptor TNFRSF4 information

Summary: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008] [NCBI] [Proteinatlas]

Data Source

Data set information

Project	Date	Technology	Tissue	Condition	Cell	PMID/DOI
Vthunter_0066	2021.04	iDrop	PBMC	Normal	12794	Link

Featureplot of receptors

mRNA expression of TNFRSF4 in human tissues [NCBI]

Expression: Broad expression in fat (RPKM 2.7), lymph node (RPKM 1.6) and 14 other tissues?

Protein expression of TNFRSF4 in human tissues [Proteinatlas]